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Displaying results 891 - 900 of 8195 in total
  1. Drug

    Elacestrant

    go.drugbank.com/drugs/DB06374
    ApprovedInvestigational

    [L44918,L44948] It received a similar approval in the EU in September 2023. … Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  2. Drug

    Ergotamine

    go.drugbank.com/drugs/DB00696
    Approved

    It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.

    Mixtures: DEGORKAF-DUO, Cafergot Pb TabCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  3. Drug

    Hepatitis B Vaccine (Recombinant)

    go.drugbank.com/drugs/DB11627
    ApprovedInvestigationalWithdrawn

    Hepatitis D virus, a defective virus requiring the “keeper function” of the hepatitis B virus, occurs either as a co-infection or super-infection in a HBsAg carrier. … The incubation period may be as long as 6 months, followed by a very complex clinical course of an acute or chronic nature, often leading to hospitalization.

  4. Drug

    Edoxudine

    go.drugbank.com/drugs/DB13421
    ApprovedWithdrawn

    The obtained product is an antiviral ointment.[L2407] The activity of edoxudine against herpes simplex virus was first recognized in 1967.

  5. Drug

    Reslizumab

    go.drugbank.com/drugs/DB06602
    ApprovedInvestigational

    Cinqair is indicated as an add-on maintenance therapy for adults with severe asthma with an eosinophilic phenotype. … Inflammation-predominant asthma, which is chatacterized by eosinophilic infiltration of airway mucosa and elevated levels of eosinophils in the blood, sputum and BAL fluid, is associated with an increased

  6. Drug

    Denileukin diftitox

    go.drugbank.com/drugs/DB00004
    ApprovedInvestigational

    [A264344] In 2014, it was withdrawn voluntarily from the market due to manufacturing issues; however, the biologics license application (BLA) for denileukin diftitox was resubmitted, and it was approved … Denileukin diftitox is an IL2-receptor-directed cytotoxin, is a recombinant DNA-derived fusion protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met<sub>1</sub>-Thr<sub

  7. Drug

    Vitamin A

    go.drugbank.com/drugs/DB00162
    ApprovedInvestigationalNutraceuticalVet approved

    Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the

    Mixtures: Ch-P Cap, P-NATAL®Products: AVIGEN DRAJE 25.000 IU, 20 ADET, CAROVIGEN 100 MG 50.000 IU DRAJE, 30 ADET
  8. Drug

    Icodextrin

    go.drugbank.com/drugs/DB00702
    ApprovedInvestigational

    Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers.

    Mixtures: SOLUCIÓN DP PISA DXT
  9. Drug

    Clonidine

    go.drugbank.com/drugs/DB00575
    ApprovedInvestigational

    Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors.[A180559] This activity is useful for the treatment of hypertension, severe pain, and ADHD.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Nu-clonidine Tab 0.2mg, Nu-clonidine Tab 0.1mg
  10. Drug

    Dutasteride

    go.drugbank.com/drugs/DB01126
    ApprovedInvestigational

    Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart.

    Mixtures: ZIVATA-DUO, ASOFLON-DUOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates