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ENB-003
go.drugbank.com/drugs/DB17340InvestigationalENB-003 is a selective and potent inhibitor of the endothelin B receptor (ETBR) being investigated for cancer.
MRT5005
go.drugbank.com/drugs/DB18260InvestigationalMRT5005 is a human cystic fibrosis transmembrane conductance regulator (hCFTR) messenger RNA (mRNA) complexed with branched polyethyleneimine (bPEI).
TCB-008
go.drugbank.com/drugs/DB18352InvestigationalTCB-008 is an Allogeneic CD3+ T lymphocyte ex vivo expanded expressing the gamma delta T-cell receptor.
FLT190
go.drugbank.com/drugs/DB18420InvestigationalFLT190 is a recombinant adeno-associated viral vector serotype S3 containing DNA encoding for human alpha-galactosidase A.
Prizloncabtagene autoleucel
go.drugbank.com/drugs/DB18623InvestigationalC-CAR039 is an autologous Chimeric Antigen Receptors (CAR) T-cell therapy expressing CD19/CD20 bi-specific CAR.
CTX120
go.drugbank.com/drugs/DB18625InvestigationalCTX120 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting B-cell maturation antigen.
Avoplacel
go.drugbank.com/drugs/DB18659InvestigationalAvoplacel (PLX-R18) is an allogeneic cell therapy under investigation for the treatment of acute radiation syndrome.[L48370]
Venanprubart
go.drugbank.com/drugs/DB18891InvestigationalVenanprubart is under investigation in clinical trial NCT05781451 (Anti-btla Agonist Therapy in Subjects With Primary Sjogren's Syndrome).
BMS-770767
go.drugbank.com/drugs/DB18902InvestigationalBMS-770767 is under investigation in clinical trial NCT01058083 (Safety Study of BMS-770767 in Subjects With Hypercholesterolemia).
Edecesertib
go.drugbank.com/drugs/DB18917InvestigationalEdecesertib is under investigation in clinical trial NCT05629208 (Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)).