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MBP134
go.drugbank.com/drugs/DB18686ExperimentalMBP134 is a pan-ebolavirus cocktail comprising two broadly neutralizing human antibodies. It is under investigation for the treatment of Sudan ebolavirus (SUDV).
Synonyms: Two immunoglobulin subclass 1 (IgG1) human monoclonal antibodies that target the Sudan ebolavirus glycoproteinBexmarilimab
go.drugbank.com/drugs/DB16383InvestigationalBexmarilimab is under investigation in clinical trial NCT03733990 (A Study to Evaluate Safety, Tolerability and Preliminary Efficacy of FP-1305 in Cancer Patients).
Synonyms: Anti-clever-1 monoclonal antibody FP-1305Lactoferrin
go.drugbank.com/drugs/DB16555InvestigationalLactoferrin is under investigation in clinical trial NCT03748043 (The Effectiveness of Lactoferrin in Treatment of Iron Deficiency Anemia in Children With Chronic Tonsillitis).
Azafenidin
go.drugbank.com/drugs/DB19031InvestigationalAzafenidin is under investigation in clinical trial NCT01726582 (Pancreas Cancer: Molecular Profiling as a Guide to Therapy Before and After Surgery ("Personalized Medicine")).
Synonyms: 2-(2,4-dichloro-5-(2-propynyloxy)phenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyridin-3(2h)-one, 2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo(4,3-a)pyridin-3(2h)-oneCAR BCMA-CS1
go.drugbank.com/drugs/DB17313ExperimentalCAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.
Synonyms: BCMA-CS1 cCAR T cell therapyNY-ESO-1 peptide vaccine
go.drugbank.com/drugs/DB17498InvestigationalNY-ESO-1 peptide vaccine is an investigational cancer immunotherapy. It contains a peptide derived from the cancer-testis antigen (NY-ESO-1).
Synonyms: NY-ESO-1 peptide vaccineEthaselen
go.drugbank.com/drugs/DB15051InvestigationalEthaselen is under investigation in clinical trial NCT02166242 (Ethaselen for the Treatment of Thioredoxin Reductase High Expression Advanced Non-small Cell Lung Cancers).
ZEN-3694
go.drugbank.com/drugs/DB22031InvestigationalZEN-3694 is under investigation in clinical trial NCT04840589 (Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors).
D-Tyrosine
go.drugbank.com/drugs/DB03839ExperimentalA non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
Synonyms: (R)-2-Amino-3-(p-hydroxyphenyl)propionic acid, (R)-3-(p-Hydroxyphenyl)alanineSenicapoc
go.drugbank.com/drugs/DB06280InvestigationalSenicapoc (ICA-17043) is a novel Gardos channel blocker.[A259068] It is being investigated for the treatment of sickle cell disease.
Synonyms: 2,2-Bis(4-fluorophenyl)-2-phenylacetamide, Bis(4-fluorophenyl)phenylacetamide