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Orvepitant
go.drugbank.com/drugs/DB12427InvestigationalOrvepitant has been used in trials studying the treatment of Depressive Disorder, Depressive Disorder, Major, Post-Traumatic Stress Disorder, and Posttraumatic Stress Disorder (PTSD).
Categories: Heterocyclic Compounds, 1-RingOltipraz
go.drugbank.com/drugs/DB12539InvestigationalOltipraz has been used in trials studying the treatment and prevention of Lung Cancer, Liver Fibrosis, Liver Cirrhosis, and Non-alcoholic Fatty Liver Disease.
Categories: Heterocyclic Compounds, 1-Ring, Compounds used in a research, industrial, or household settingLexaptepid pegol
go.drugbank.com/drugs/DB12578InvestigationalLexaptepid pegol has been used in trials studying the treatment of Anemia, Inflammation, Chronic Diseases, End Stage Renal Disease, and Anemia of Chronic Disease.
Etalocib
go.drugbank.com/drugs/DB12850InvestigationalEtalocib has been used in trials studying the treatment of Pancreatic Cancer, Carcinoma, Non-Small-Cell Lung, and Unspecified Adult Solid Tumor, Protocol Specific.
IFx-Hu2.0
go.drugbank.com/drugs/DB18396InvestigationalIFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Synonyms: Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein, complexed with in vivo-jetPEI® polymer-based reagent linearNDX-3315
go.drugbank.com/drugs/DB18671InvestigationalNDX-3315 is an investigational radiopharmaceutical agent for the diagnosis, treatment monitoring, and management of eosinophilic esophagitis. It is a technetium-99m radiolabeled [heparin].
AG0302-COVID19
go.drugbank.com/drugs/DB16435InvestigationalSponsored by Anges, Inc. in Japan, the AG0302-COVID19 is a DNA-based vaccine that recently completed Phase I/II trials (NCT04527081)[A226813, L30548].
Sutetinib
go.drugbank.com/drugs/DB18841InvestigationalSutetinib is under investigation in clinical trial NCT05168566 (Study to Evaluate Sutetinib Maleate Capsule in Locally Advanced or Metastatic Non-small Cell Lung Cancer).
Synonyms: (2e)-n-(3-cyano-7-ethoxy-4-((3-ethynylphenyl)amino)-6-quinolinyl)-4-(dimethylamino)-2-butenamide, 2-butenamide, n-(3-cyano-7-ethoxy-4-((3-ethynylphenyl)amino)-6-quinolinyl)-4-(dimethylamino)-, (2e)-Palazestrant
go.drugbank.com/drugs/DB18971InvestigationalPalazestrant is under investigation in clinical trial NCT06016738 (OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer).
Synonyms: (1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-1-{4-[(1-propylazetidin-3- yl)oxy]phenyl}-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole, 1H-Pyrido[3,4-b]indole, 2-(2-fluoro-2-methylpropyl)-2,3,4,9-tetrahydro-3-methyl-1-[4-[(1-propyl-3-azetidinyl)oxy]phenyl]-, (1R,3R)-IP-2018
go.drugbank.com/drugs/DB19049InvestigationalIP-2018 is under investigation in clinical trial NCT04686916 (Clinical Trial Studying the Efficacy and Safety of IP2018 in Depressed, Erectile Dysfunction (ED) Patients).
Synonyms: 2h-1-benzopyran-2-one, 7-((3-exo)-8-azabicyclo(3.2.1)oct-3-yloxy)-, 7-((3-exo)-8-azabicyclo(3.2.1)oct-3-yloxy)-2h-1-benzopyran-2-one