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Tretamine
go.drugbank.com/drugs/DB14031ExperimentalToxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
Selicrelumab
go.drugbank.com/drugs/DB14958InvestigationalSelicrelumab is under investigation in clinical trial NCT01008527 (Phase I Oncovir Poly IC:LC and NY-ESO-1/gp100).
Agerafenib
go.drugbank.com/drugs/DB15068InvestigationalAgerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations).
Ravidasvir
go.drugbank.com/drugs/DB15652InvestigationalRavidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection).
anti-OX40 antibody BMS 986178
go.drugbank.com/drugs/DB15773InvestigationalA macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.
Ibezapolstat
go.drugbank.com/drugs/DB16189InvestigationalIbezapolstat is under investigation in clinical trial NCT04247542 (ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection).
Izencitinib
go.drugbank.com/drugs/DB16660InvestigationalIzencitinib is under investigation in clinical trial NCT03920254 (TD-1473 Long-term Safety (LTS) Ulcerative Colitis (UC) Study).
Autologous DNP-conjugated tumour vaccine
go.drugbank.com/drugs/DB17361InvestigationalAutologous DNP-conjugated tumour vaccine, or melanoma vaccine, is an investigational autologous cell vaccine technology for melanoma.[A254806]
Trotabresib
go.drugbank.com/drugs/DB17421InvestigationalTrotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal (BET) proteins.
OPC1
go.drugbank.com/drugs/DB17944ExperimentalOPC1 is an oligodendrocyte progenitor cell therapy being investigated for the treatment of acute spinal cord injury.[L47082]