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AVR-RD-01
go.drugbank.com/drugs/DB17651InvestigationalIt consists of autologous CD34+ cells that transduced with Lentiviral Vector/alpha-galactosidase A (AGA) encoding for the human AGA complementary deoxyribonucleic acid (cDNA) sequence.
ATG-101
go.drugbank.com/drugs/DB17162InvestigationalATG-101 is a novel PD-L1/4-1BB bispecific antibody that was designed to block the binding of immunosuppressive PD-1/PD-L1 and conditionally induce 4-1BB stimulation, thus activating anti-tumor immune effectors
Asapiprant
go.drugbank.com/drugs/DB20492InvestigationalAsapiprant has a monoisotopic molecular weight of 501.16 Da.
Alofanib
go.drugbank.com/drugs/DB20918InvestigationalAlofanib has a monoisotopic molecular weight of 413.07 Da.
Serelaxin
go.drugbank.com/drugs/DB05794Investigationalis a hormone produced during pregnancy that facilitates the birth process by causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic bones come together).It
BGB-DXP593
go.drugbank.com/drugs/DB16357Investigational[L27401] It is currently being investigated against COVID-19 in the clinical trial NCT04551898 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants
Devafidugene civaparvovec
go.drugbank.com/drugs/DB16790InvestigationalIt uses proprietary zinc finger nucleases (ZFN) that insert a functional copy of the alpha-L-iduronidase (IDUA) enzyme.
NGN-401
go.drugbank.com/drugs/DB18594InvestigationalDeveloped by Neurogene Inc., it is being investigated for the treatment of Rett syndrome.
AZD2389
go.drugbank.com/drugs/DB22104Investigational[L54978] It is currently undergoing safety, tolerability, and PK/PD profiling in clinical trials (e.g.
WNY0824
go.drugbank.com/drugs/DB23606Experimental[A274253] It is a dual inhibitor of PLK-1 and BRET-4, which have both been found to be involved in CRPC via suppression of AR/MYC-mediated transcription. [A274258]