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MaaT013
go.drugbank.com/drugs/DB18648InvestigationalMaaT013 is an allogeneic fecal microbiota therapy. It is being investigated for the treatment of Graft-Versus-Host Disease.
ECT-001 expanded cord blood
go.drugbank.com/drugs/DB21745Investigational[L52013] It is being investigated in hematopoietic cell transplantation as ECT-001 expanded cord blood can demonstrate enhanced stem cell proliferation and engraftment compared to untreated UBCs. … ECT-001 expanded cord blood is umbilical cord blood (UCB) that has been co-cultured and expanded with the small molecule agonist [UM-171].
Deslorelin
go.drugbank.com/drugs/DB11510InvestigationalVet approvedDeslorelin acetate is an injectable gonadotropin releasing hormone super-agonist also known as an LHRH agonist. It stops the production of sex hormones.
ATR-04
go.drugbank.com/drugs/DB26782InvestigationalATR-04 is a biologic drug. ATR-04 is under investigation in clinical trial NCT04731259 (Study to Evaluate the Safety of ATR-04).
Coronavirus-Like Particle COVID-19 Vaccine
go.drugbank.com/drugs/DB15852ExperimentalThe Coronavirus-Like Particle COVID-19 Vaccine is in development and testing through Meidcago in Quebec City, Canada. … A Phase 1 clinical trial was launched in July 2020 evaluating the safety, tolerability, and immunogenicity of this vaccine candidate with or without either Cpg 1018 or AS03 (NCT04450004) in adults aged
Myrcludex B
go.drugbank.com/drugs/DB14853InvestigationalMyrcludex B is under investigation in clinical trial NCT03546621 (A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination … With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D).
VIR-5500
go.drugbank.com/drugs/DB28578InvestigationalVIR-5500 is a small molecule drug. VIR-5500 is under investigation in clinical trial NCT05997615 (Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer).
GX-19 Vaccine
go.drugbank.com/drugs/DB15891InvestigationalThe GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea[A219758]. … As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].
DTX-101
go.drugbank.com/drugs/DB17699InvestigationalDTX-101 is an investigational gene therapy consisting of an adeno-associated virus serotype Rh10 vector encoding the human Factor Ix gene. … It was previously investigated for the treatment of hemophilia B; however, the clinical development of DTX-101 was discontinued.[L46103]
Retezorogant
go.drugbank.com/drugs/DB21592ExperimentalThe usage of the INN stem '-rogant' in the name indicates that Retezorogant is a retinoic acid receptor-related orphan receptor gamma (RORY) antagonist and inverse agonist. … Retezorogant is a small molecule drug.