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Displaying results 9251 - 9260 of 10000 in total
  1. Drug

    Ianalumab

    go.drugbank.com/drugs/DB16666
    Investigational

    Ianalumab is under investigation in clinical trial NCT01930175 (Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris).

  2. Drug

    Surzebiclimab

    go.drugbank.com/drugs/DB16669
    Investigational

    Surzebiclimab is under investigation in clinical trial NCT03744468 (Study of BGB-A425 in Combination With Tislelizumab in Advanced Solid Tumors).

  3. Drug

    PXT 3003

    go.drugbank.com/drugs/DB16745
    Investigational

    PXT 3003 is in phase 3 clinical trials for the treatment of Charcot-Marie-Tooth disease type 1A in adults.

  4. Drug

    Domofenogene zalfaparvovec

    go.drugbank.com/drugs/DB16810
    Investigational

    Domofenogene zalfaparvovec, formerly known as BMN-307, is an investigational AAV5-phenylalanine hydroxylase (PAH) gene therapy developed by BioMarin Pharmaceutical.

  5. Drug

    AT-GTX-502

    go.drugbank.com/drugs/DB17001
    Experimental

    AT-GTX-502 is an experimental, one-time gene therapy that uses AAV9 to deliver a functional copy of CLN3.

    Categories: Non-Replicating Recombinant, Self-Complementary Adeno-Associated Virus Serotype 9 Containing the Human CLN3 Gene
  6. Drug

    AMZ002

    go.drugbank.com/drugs/DB17017
    Investigational

    AMZ002 is a sterile injectable hormone developed as a purified synthetic polypeptide alternative to current FDA-approved epileptic seizure treatments.

  7. Drug

    Xaluritamig

    go.drugbank.com/drugs/DB18137
    Investigational

    Xaluritamig is a novel humanized bispecific T cell recruiting antibody cross-reactive to human and nonhuman primate STEAP1 and CD3.

    Synonyms: immunoglobulin G1-scFv-CH/G1-kappa, anti-[Homo sapiens STEAP1 (STEAP family member 1, six transmembrane epithelial antigen of the prostate 1, STEAP1 metalloreductase) and anti-[Homo sapiens CD3, bispecific, Immunoglobulin G1 Fab fragment [218-lysine], anti-(human metalloproteinase STEAP1) (human-Mus musculus clone 2F3.013 N67Q γ1-chain) fusion protein with peptide linker (GGGGS)2 fusion protein with immunoglobulin
  8. Drug

    TSHA-105

    go.drugbank.com/drugs/DB18328
    Investigational

    TSHA-105 is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human SLC13A5 protein.

  9. Drug

    RC118

    go.drugbank.com/drugs/DB18428
    Investigational

    RC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.

    Synonyms: Recombinant humanized anti-MSLN monoclonal antibody- monomethyl auristatin E conjugate
  10. Drug

    TRK-250

    go.drugbank.com/drugs/DB18500
    Investigational

    TRK-250 is a small interfering RNA agent that targets human transforming growth factor-beta 1 (TGF-β1) messenger RNA.