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Displaying results 9251 - 9260 of 10000 in total

Drug
GSK-256066
go.drugbank.com/drugs/DB12137
Investigational
Gsk256066 has been used in trials studying the treatment and diagnostic of SAR, Asthma, Mild Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis, among others.
Categories: Heterocyclic Compounds, 2-Ring, Phosphodiesterase 4 Inhibitors
Drug
AZD-0328
go.drugbank.com/drugs/DB12145
Investigational
AZD0328 has been used in trials studying the treatment and basic science of Schizophrenia and Alzheimer's Disease.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Menatetrenone
go.drugbank.com/drugs/DB12148
Investigational
Menatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma.
Categories: Vitamin K
Drug
Brincidofovir
go.drugbank.com/drugs/DB12151
ApprovedInvestigational
[A235725,A235735] Due to its formulation as a pro-drug brincidofovir also carries a greater bioavailability than cidofovir,[A235740,A235725] allowing for oral administration rather than intravenous. … The approval was granted under the agency’s Animal Rule,[L34480] which allows for a drug to be approved based on the results of well-controlled animal studies when human trials would be unethical or infeasible
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Heterocyclic Compounds, 1-Ring
Drug
Citicoline
go.drugbank.com/drugs/DB12153
ApprovedInvestigationalWithdrawn
Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides.
Categories: Heterocyclic Compounds, 1-RingSynonyms: citidin difosfato de colina, Cytidine 5'-diphosphocholine
Drug
Napabucasin
go.drugbank.com/drugs/DB12155
Investigational
Napabucasin has been investigated for the treatment of Colorectal Carcinoma.
Categories: Heterocyclic Compounds, 2-Ring
Drug
Fasinumab
go.drugbank.com/drugs/DB12157
Investigational
Fasinumab is a human IgG1k monoclonal antibody targeted against nerve growth factor (NGF). … [A241165] NGF was first discovered in the 1950s[A241180] and was the first neurotrophic factor to be identified and biochemically characterized.
Drug
Filorexant
go.drugbank.com/drugs/DB12158
Investigational
Filorexant has been used in trials studying the prevention and treatment of Migraine, Headache, Polysomnography, Diabetic Neuropathy, Painful, and Major Depressive Disorder, Recurrent.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Deutetrabenazine
go.drugbank.com/drugs/DB12161
ApprovedInvestigational
It is a hexahydro-dimethoxybenzoquinolizine derivative and a deuterated [DB04844] [A32046]. … This allows less frequent dosing and a lower daily dose with improvement in tolerability [A32043].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
Drug
Nimorazole
go.drugbank.com/drugs/DB12172
Investigational
Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
Categories: Heterocyclic Compounds, 1-Ring