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Gimatecan
go.drugbank.com/drugs/DB06721InvestigationalGimatecan is an orally available 7-t-butoxyiminomethyl-substituted lipophilic camptothecin derivative.
Synonyms: (4S)-11-[(E)-(tert-butoxyimino)methyl]-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, (4S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1-H-pyrano[3',4':6,7]-indolizino-[1,2-b]-quinoline-11-carbaldehyde O-(tert-butyl)-(E)-oximeIR208
go.drugbank.com/drugs/DB05106InvestigationalIR208 is a synthetic T-Cell receptor peptide vaccine developed by Immune Response Corporation. … It contains three peptides (BV5S2, BV6S5 and BV13S1) expressed by T-Cells in over 90% of MS patients. IR208 is currently undergoing Phase II studies in a 200-patient trial.
PHE885
go.drugbank.com/drugs/DB18123InvestigationalPHE885 is an investigational, autologous B-cell Maturation Antigen (BCMA)-directed chimeric antigen receptor (CAR)-T cell therapy.
CT103A
go.drugbank.com/drugs/DB18180InvestigationalCT103A is an investigational BCMA-targeted genetically modified autologous T-cell immunotherapy.
CT120
go.drugbank.com/drugs/DB18181InvestigationalCT120 is an investigational autologous CD19/22 targeted CAR-T cell immunotherapy.
SMART101
go.drugbank.com/drugs/DB18370InvestigationalSMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors that were cultured ex vivo.
RAPA-201
go.drugbank.com/drugs/DB18446InvestigationalRAPA-201 is an autologous rapamycin-resistant T-cell therapy.
Synonyms: Rapamycin-resistant autologous Th1/Tc1 T-cellsASP-2138
go.drugbank.com/drugs/DB18473InvestigationalASP-2138 is a bispecific antibody directed against CLDN18.2 and T cell receptor complex CD3
PA3-17
go.drugbank.com/drugs/DB18569InvestigationalPA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy.
Synonyms: Chimeric Antigen Receptor T Cells targeting CD7CTX130
go.drugbank.com/drugs/DB18627InvestigationalCTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Synonyms: Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigen