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INT41
go.drugbank.com/drugs/DB17935ExperimentalINT41 (also known as rAAV6-INT41) is a recombinant adeno-associated virus vector containing DNA encoding INT41 intrabody.
NGN-101
go.drugbank.com/drugs/DB18335InvestigationalNGN-101 is an adeno-associated virus serotype 9 vector with engineered transgene encoding the human CLN5 gene
ECT204
go.drugbank.com/drugs/DB18605InvestigationalECT204 is an autologous T-cell therapy whereby T cells are genetically modified to target tumor-specific antigens.
Tusamitamab ravtansine
go.drugbank.com/drugs/DB17448InvestigationalTusamitamab ravtansine is an antibody-drug conjugate that targets carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5).
CX157
go.drugbank.com/drugs/DB05205InvestigationalMAO-A inhibitors of this class. … CX157,3-fluoro-7-(2,2,2,-trifluoroethoxy)phenoxathiin-10,10-dioxide, is a reversible, selective inhibitor of MAO-A designed to have improved oral bioavailability and reduced clearance compared to previous
Talactoferrin alfa
go.drugbank.com/drugs/DB05426InvestigationalIt increases body’s immune power and also works as a natural antioxidant, helping to control cell and tissue damage caused by oxidation. … Talactoferrin alfa is a novel immunomodulatory 80 kD protein with demonstrated oral anti-tumor properties. Lactoferrin, a protein found in breast milk is developed by Agennix.
Gataparsen
go.drugbank.com/drugs/DB05141InvestigationalLY2181308 is a solid. LY2181308 is directed against a molecular target called survivin. LY2181308 is known to target baculoviral IAP repeat-containing protein 5. … LY2181308 is an anti-sense oligonucleotide that potently downregulated survivin expression in human cancer cells derived from lung, colon, breast, prostate, ovary, cervix, skin and brain.
PRGN-3006
go.drugbank.com/drugs/DB17229InvestigationalPRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface
Synonyms: Autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane bound Interleukin-15, and a truncated form of human HER1t (kill switch) on the cell surfaceNBF-006
go.drugbank.com/drugs/DB21770InvestigationalNBF-006 is under investigation in clinical trial NCT03819387 (A Study of NBF-006 in Non-small Cell Lung, Pancreatic, or Colorectal Cancer). … This drug is a proprietary siRNA-based lyophilized lipid nanoparticle (LNP).[A273775, L52905]
1-benzylimidazole
go.drugbank.com/drugs/DB04581Experimental1-benzylimidazole, an N-imidazole derivative, has been shown to have strong cardiotonic activity.