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Buntanetap
go.drugbank.com/drugs/DB15317InvestigationalBuntanetap (previously known as Posiphen) is under investigation in clinical trial NCT02925650 (Safety, Tolerability, PK and PD of Posiphen® in Subjects With Early Alzheimer's Disease).
Categories: Heterocyclic Compounds, 2-RingNacubactam
go.drugbank.com/drugs/DB15353InvestigationalNacubactam is under investigation in clinical trial NCT03174795 (A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection).
Categories: Heterocyclic Compounds, 1-RingCerdulatinib
go.drugbank.com/drugs/DB15499InvestigationalCerdulatinib is under investigation in clinical trial NCT04021082 (CELTIC-1: A Phase 2B Study of Cerdulatinib in Patients With Relapsed/refractory Peripheral T-cell Lymphoma (PTCL)).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-(cyclopropylamino)-2-((4-(4-(ethanesulfonyl)piperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide, 5-pyrimidinecarboxamide, 4-(cyclopropylamino)-2-((4-(4-(ethylsulfonyl)-1-piperazinyl)phenyl)amino)-NCX-1000
go.drugbank.com/drugs/DB16026InvestigationalNCX-1000 is under investigation in clinical trial NCT00414869 (Preliminary Efficacy and Tolerability of NCX-1000 After Repeated Oral Doses in Patients With Elevated Portal Pressure).
Firmonertinib
go.drugbank.com/drugs/DB16087InvestigationalAlflutinib is under investigation in clinical trial NCT03452592 (Efficacy and Safety of Alflutinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer Patients With T790M).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSimlukafusp alfa
go.drugbank.com/drugs/DB16092InvestigationalRO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic
Synonyms: Anti-fap/interleukin-2 fusion protein ro6874281Deferitrin
go.drugbank.com/drugs/DB16132InvestigationalDeferitrin is under investigation in clinical trial NCT00069862 (Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-thalassemia).
Categories: Heterocyclic Compounds, 1-RingEcraprost
go.drugbank.com/drugs/DB16148InvestigationalEcraprost is under investigation in clinical trial NCT00059657 (Efficacy/safety of Ecraprost in Lipid Emulsion for Treatment of Critical Leg Ischemia Due to Peripheral Arterial Disease).
Indatuximab ravtansine
go.drugbank.com/drugs/DB16195InvestigationalIndatuximab ravtansine is under investigation in clinical trial NCT01001442 (Safety and Dose Determining Multi-dose Study of BT062 in Patients With Relapsed or Refractory Multiple Myeloma).
Synonyms: N2'-Deacetyl-N2'-[4-Methyl-4-(Oxobuthyldithio)-1-Oxopentyl]-Maytansine-Chimerized Anti-Cd138 Igg4 Monoclonal AntibodyLadarixin
go.drugbank.com/drugs/DB16212InvestigationalLadarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function).