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GTB-3550
go.drugbank.com/drugs/DB18494InvestigationalGTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form
Synonyms: single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 scFV with a modified IL-15 linkerAPR-2020
go.drugbank.com/drugs/DB18497InvestigationalAPR-2020 is a CD34+ cells that have been transduced in vitro with a lentiviral vector carrying a codon-optimized sequence for expressing the wild type RPS19 protein
TRK-250
go.drugbank.com/drugs/DB18500InvestigationalTRK-250 is a small interfering RNA agent that targets human transforming growth factor-beta 1 (TGF-β1) messenger RNA.
RAG-17
go.drugbank.com/drugs/DB18503InvestigationalRAG-17 is a siRNA oligonucleotide designed to target and knockdown the expression of superoxide dismutase (SOD).
CEB-01
go.drugbank.com/drugs/DB18505InvestigationalCEB-01 is a biocompatible polymeric PLGA nanofiber membrane containing the active substance 7-ethyl-10-hydroxycamptothecin
NTLA-2001
go.drugbank.com/drugs/DB18525InvestigationalNTLA-2001 is a clustered regularly interspaced short palindromic repeats CRISPR/ Cas9-based gene therapy consisting of a single guide RNA targeting the human TTR gene and a messenger RNA encoding Cas9.
Cytochrome C
go.drugbank.com/drugs/DB18543InvestigationalCytochrome C is a hemeprotein that plays a role in the mitochondrial electron-transport chain.
SIG-205
go.drugbank.com/drugs/DB18548ExperimentalSIG-205 is a Cultured human retinal pigment epithelial cells (ARPE-19) genetically modified with a non-viral vector to express human native alpha-L-iduronidase enzyme (hIDUA), encapsulated within two-layer
ISB 2001
go.drugbank.com/drugs/DB18570InvestigationalISB 2001 is a T cell-engaging antibody that targets BCMA, CD38, and CD3.