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Bamocaftor
go.drugbank.com/drugs/DB15177InvestigationalBamocaftor (VX-659) is under investigation in clinical trial NCT03224351 (A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis).
Synonyms: 3-Pyridinecarboxamide, N-(phenylsulfonyl)-6-(3-(2-(1-(trifluoromethyl)cyclopropyl)ethoxy)-1H-pyrazol-1-yl)-2-((4S)-2,2,4-trimethyl-1-pyrrolidinyl)-, N-(benzenesulfonyl)-6-[3-[2-[1-(trifluoromethyl)cyclopropyl]ethoxy]pyrazol-1-yl]-2-[(4S)-2,2,4-trimethylpyrrolidin-1-yl]pyridine-3-carboxamideGiripladib
go.drugbank.com/drugs/DB15426InvestigationalGiripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee).
(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide
go.drugbank.com/drugs/DB06941ExperimentalThis compound belongs to the phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group. This drug targets the protein S100B.
4-(4-fluoro-phenylazo)-5-imino-5H-pyrazol-3-ylamine
go.drugbank.com/drugs/DB08667ExperimentalThis compound belongs to the fluorobenzenes. These are compounds containing one or more fluorine atoms attached to a benzene ring. This substance targets the protein methionine aminopeptidase.
HNF4α srRNA
go.drugbank.com/drugs/DB27228InvestigationalHNF4α srRNA is under investigation in clinical trial NCT06583993 (A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α srRNA in Treating Advanced ICC Patients).
BMS-986263
go.drugbank.com/drugs/DB28821InvestigationalBMS-986263 is under investigation in clinical trial NCT04267393 (Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)).
Synonyms: ND-L02-s0201CHGN111
go.drugbank.com/drugs/DB06376ExperimentalCHGN111 is an inhibitor of the mitochondrial enzyme CLK-1 which is a demethoxyubiquinone hydroxylase.
Fiztasovimab
go.drugbank.com/drugs/DB24033InvestigationalFiztasovimab, also known as NPC‐21 and EV2038, is a monoclonal antibody.
Etriciguat
go.drugbank.com/drugs/DB20610ExperimentalThe usage of the INN stem '-ciguat' in the name indicates that Etriciguat is a guanylate cyclase activator and stimulator. Etriciguat has a monoisotopic molecular weight of 397.15 Da.