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Silmitasertib
go.drugbank.com/drugs/DB15408InvestigationalSilmitasertib is under investigation in clinical trial NCT03904862 (Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery).
2-(5-fluoro-pentyl)-2-methyl-malonic-acid
go.drugbank.com/drugs/DB16029Investigational2-(5-fluoro-pentyl)-2-methyl-malonic-acid is under investigation in clinical trial NCT00696943 (18F ML-10 for Early Detection of Response of Brain Metastases to SRS).
Sepofarsen
go.drugbank.com/drugs/DB16327InvestigationalSepofarsen is under investigation in clinical trial NCT03913143 (A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)).
Tafolecimab
go.drugbank.com/drugs/DB16336InvestigationalTafolecimab is under investigation in clinical trial NCT04031742 (A Study to Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia
Zampilimab
go.drugbank.com/drugs/DB16381InvestigationalZampilimab is under investigation in clinical trial NCT04335578 (A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of UCB7858 in Adult Kidney Transplant Recipients With Chronic Allograft
APR-2020
go.drugbank.com/drugs/DB18497InvestigationalAPR-2020 is a CD34+ cells that have been transduced in vitro with a lentiviral vector carrying a codon-optimized sequence for expressing the wild type RPS19 protein
LMB-100
go.drugbank.com/drugs/DB18591InvestigationalLMB-100 is a is an antibody-toxin conjugate with an antimesothelin Fab linked to a 24-kilodalton portion of Pseudomonas exotoxin A with mutations that decrease immunogenicity.
Visugromab
go.drugbank.com/drugs/DB18894InvestigationalVisugromab is under investigation in clinical trial NCT06059547 (Neoadjuvant Immunotherapy in Combination With the Anti-gdf-15 Antibody Visugromab (CTL-002) for Treatment of Muscle Invasive Bladder Cancer
Bosakitug
go.drugbank.com/drugs/DB19101InvestigationalBosakitug (BSI-045B) is under investigation in clinical trial NCT05932654 (POC Study to Evaluate BSI-045B Monotherapy and BSI-045B Add-on Therapy With Dupilumab in Atopic Dermatitis).
GB-115
go.drugbank.com/drugs/DB19204InvestigationalGB-115 is under investigation in clinical trial NCT05586789 (A Study of the Efficacy and Safety of Ranquilon Tablets in Patients With Anxiety in Neurasthenia and Adjustment Disorders).