Search

Displaying results 9651 - 9660 of 10000 in total
  1. Drug

    EGT-201

    go.drugbank.com/drugs/DB17648
    Experimental

    EGT-201 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the alpha-N-acetyglucosaminidase (NAGLU) transgene. … Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type B.[L45939]

  2. Drug

    Difloxacin

    go.drugbank.com/drugs/DB11511
    ExperimentalVet approved

    However, it presents a reduced efficacy when compared to other fluoroquinolone antibacterials. … Difloxacin is a synthetic fluoroquinolone used in veterinary. As an antibacterial, it presents a broad bactericidal spectrum and its effects are dependent on its concentration.

    Categories: 4-Quinolones, Cytochrome P-450 Substrates
  3. Drug

    Lapyrium

    go.drugbank.com/drugs/DB09376
    Approved

    Lapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various cosmetic products [A19426]. It is commonly found formulated as lapyrium chloride.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Inactivated SARS-Cov-2 Vaccine

    go.drugbank.com/drugs/DB15862
    Investigational

    [A220158] Currently, the vaccine is being tested in Phase 3 clinical trial in Abu Dhabi (ChiCTR2000034780).[A219758] … Developed by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 strain of SARS-CoV-2.

  5. Drug

    Oxabolone cipionate

    go.drugbank.com/drugs/DB13185
    Experimental

    Oxabolone cipionate is the C17β cypionate ester and a prodrug of [DB01500]. A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone). … It is considered as a performance enhancing drug thus is prohibited from use in sports.

    Synonyms: Cipionato de oxabolona, 4-hydroxy-19-nortestosterone 17β-cypionate
  6. Drug

    NSI-566

    go.drugbank.com/drugs/DB17954
    Investigational

    Developed by Seneca Biopharma, it is being investigated for the treatment of amyotrophic lateral sclerosis (ALS), stroke, and chronic spinal cord injury (cSCI).[L47097] … NSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells.

  7. Drug

    Drozitumab

    go.drugbank.com/drugs/DB19106
    Investigational

    It was developed by Genentech as a drug for the treatment of cancers … Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), a member of tumor necrosis factor related apoptosis-inducing ligand (TRAIL)

    Synonyms: Immunoglobulin g1, anti-(human citokine receptor dr5 (death receptor 5)) (human monoclonal heavy chain), disulfide with human l3-chain, dimer
  8. Drug

    Growth hormone-releasing peptide 1

    go.drugbank.com/drugs/DB19259
    Investigational

    Growth hormone-releasing peptide 1 is under investigation in clinical trial NCT00381602 (A Phase II, Randomized, Cross-over, Vehicle-controlled, Double-blind, Multicenter Study of the Safety, Pharmacodynamics … , and Preliminary Efficacy of GHRP-1/AG in Subjects With ESRD on Hemodialysis).

    Synonyms: L-alanyl-l-histidyl-3-(2-naphthalenyl)-d-alanyl-l-alanyl-l-tryptophyl-d-phenylalanyl-l-lysinamide, Ala-his-3-(2-naphthalenyl)-d-ala-ala-trp-d-phe-lys-nh2
  9. Drug

    Tralesinidase alfa

    go.drugbank.com/drugs/DB17657
    Investigational

    It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.[A258828] … Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2.

    Categories: beta-N-AcetylhexosaminidasesSynonyms: Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein, Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2
  10. Drug

    Dibromothymoquinone

    go.drugbank.com/drugs/DB04646
    Experimental

    At higher concentrations, it acts as an electron acceptor, intercepting electrons either before or at the site of its inhibitory activity. [PubChem] … At low concentrations, this compound inhibits reduction of conventional hydrophilic electron acceptors, probably acting as a plastoquinone antagonist.

    Synonyms: 2,5-dibromo-3-methyl-6-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione, 2,5-dibromo-3-methyl-6-(1-methylethyl)cyclohexa-2,5-diene-1,4-dione