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Displaying results 9691 - 9700 of 9860 in total
  1. Drug

    Vanzacaftor

    go.drugbank.com/drugs/DB18373
    ApprovedInvestigational

    ], a CFTR potentiator, for the treatment of patients with responsive CFTR mutations. … Vanzacaftor is a small molecule cystic fibrosis transmembrane conductance regulator (CFTR) corrector.

  2. Drug

    TORL-2-307

    go.drugbank.com/drugs/DB18376
    Experimental

    TORL-2307 is a humanized immunoglobulin G1 (IgG1) monoclonal antibody (mAb) directed against claudin 18.2 (CLDN18.2) being investigated for the treatment of gastric and pancreatic cancer.

  3. Drug

    XTMAB-16

    go.drugbank.com/drugs/DB18380
    Investigational

    XTMAB-16 is a monoclonal antibody directed against tumour necrosis factor-alpha (TNFα).

  4. Drug

    IVT-8086

    go.drugbank.com/drugs/DB18381
    Experimental

    IVT-8086 is a humanized secreted frizzled-related protein-2 monoclonal antibody.

  5. Drug

    CAN-106

    go.drugbank.com/drugs/DB18389
    Investigational

    CAN-106 a novel, long-acting monoclonal antibody directed against human complement C5.

  6. Drug

    LAVA-051

    go.drugbank.com/drugs/DB18395
    Investigational

    LAVA-051 is a humanized Vγ9Vδ2-T cell-engaging bispecific antibody.

  7. Drug

    IFx-Hu2.0

    go.drugbank.com/drugs/DB18396
    Investigational

    It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.

    Synonyms: Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic, streptococcal Emm55 protein, complexed with in vivo-jetPEI® polymer-based reagent linear
  8. Drug

    KP1237

    go.drugbank.com/drugs/DB18401
    Experimental

    KP1237 is a antibody-redirecting molecule composed of two binding sites (a CD38 binder and a universal antibody binding terminus binder) connected by a linker chain.

  9. Drug

    rAAV9-hNAGLU

    go.drugbank.com/drugs/DB18415
    Experimental

    rAAV9-hNAGLU consists of a recombinant AAV9 expressing human alpha-N-acetylglucosaminidase.

  10. Drug

    PF-05230907

    go.drugbank.com/drugs/DB18417
    Investigational

    PF-05230907 is a recombinant activated Factor X variant.

    Synonyms: RECOMBINANT FACTOR XA VARIANT FXAI16L