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Displaying results 9771 - 9780 of 10000 in total
  1. Drug

    Ebastine

    go.drugbank.com/drugs/DB11742
    ApprovedInvestigationalWithdrawn

    Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: EVASTEL Z, PINAVALT® SOLUCION
  2. Drug

    Barasertib

    go.drugbank.com/drugs/DB11747
    Investigational

    Barasertib has been used in trials studying the treatment of Tumors, Lymphoma, Solid Tumors, Solid Tumours, and Myeloid Leukemia, among others.

    Categories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Benfotiamine

    go.drugbank.com/drugs/DB11748
    ApprovedInvestigationalWithdrawn

    Benfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2.

    Synonyms: S-benzoylthiamine monophosphateCategories: Vitamin B Complex, Heterocyclic Compounds, 1-Ring
  4. Drug

    Arpraziquantel

    go.drugbank.com/drugs/DB11749
    Investigational

    (R)-Praziquantel is under investigation in clinical trial NCT02271984 (Relative Bioavailability Trial of L-Praziquantel in Healthy Volunteers).

    Synonyms: L-PZQ, L-praziquantel
  5. Drug

    Clobetasol

    go.drugbank.com/drugs/DB11750
    ApprovedInvestigationalWithdrawn

    Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: CLARELUX 500UG/G SCHAU, CLARELUX 500UG/G SCHAUM
  6. Drug

    Talazoparib

    go.drugbank.com/drugs/DB11760
    ApprovedInvestigational

    Talazoparib is an inhibitor of mammalian polyadenosine 5’-diphosphoribose polymerases (PARPs), enzymes responsible for regulating essential cellular functions, such as DNA transcription and DNA repair.

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein substrates
  7. Drug

    Tenapanor

    go.drugbank.com/drugs/DB11761
    ApprovedInvestigational

    a novel alternative in the treatment of IBS-C. … Tenapanor is a novel, small molecule medication approved in September 2019 for the treatment of constipation-predominant irritable bowel-syndrome (IBS-C).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    Momelotinib

    go.drugbank.com/drugs/DB11763
    ApprovedInvestigational

    Momelotinib is a Janus Kinase 1 (JAK1) and 2 (JAK2) inhibitor. It is a competitive inhibitor of JAK ATP binding. … [L48186] Myelofibrosis (MF) is a group of myeloproliferative neoplasms characterized by abnormal proliferative hematopoietic stem cells, leading to the release of cytokines and growth factors.

    Synonyms: N-(CYANOMETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDECategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  9. Drug

    Funapide

    go.drugbank.com/drugs/DB11769
    Investigational

    Funapide has been used in trials studying the treatment of Pharmacokinetics, Postherpetic Neuralgia, and Osteoarthritis of the Knee.

    Categories: Heterocyclic Compounds, 2-Ring
  10. Drug

    BMS-903452

    go.drugbank.com/drugs/DB11773
    Investigational

    BMS-903452 has been used in trials studying the treatment of Diabetes.

    Categories: Heterocyclic Compounds, 1-Ring