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Displaying results 9771 - 9780 of 10000 in total

Drug
Litoxetine
go.drugbank.com/drugs/DB15038
Investigational
Litoxetine is under investigation in clinical trial NCT03397771 (DBPC Trial to Evaluate the Safety, Tolerability and Efficacy of Oral Litoxetine in Subjects With Urinary Incontinence).
Categories: Heterocyclic Compounds, 1-Ring
Drug
TP-271
go.drugbank.com/drugs/DB15040
Investigational
TP-271 is under investigation in clinical trial NCT02724085 (A Phase 1 Study to Assess the Safety, Tolerability and PK of IV TP-271).
Drug
Neopterin
go.drugbank.com/drugs/DB15050
Investigational
Neopterin is under investigation in clinical trial NCT02974192 (Neopterin Effects on Ischemic Stroke).
Categories: Heterocyclic Compounds, 2-Ring
Drug
Inarigivir
go.drugbank.com/drugs/DB15062
Investigational
Inarigivir is under investigation in clinical trial NCT03434353 (Study to Evaluate the Antiviral Activity of Inarigivir (GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B
Drug
PF-06291874
go.drugbank.com/drugs/DB15065
Investigational
PF-06291874 is under investigation in clinical trial NCT02175121 (Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study of PF-06291874 as Oral Monotherapy To Treat Adults With Type 2 Diabetes
Categories: Heterocyclic Compounds, 1-Ring
Drug
Givosiran
go.drugbank.com/drugs/DB15066
Approved
Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway. … [L10202] It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic disorder
Categories: Heterocyclic Compounds, 1-Ring, Aminolevulinate Synthase 1-directed RNA Interaction
Drug
Agerafenib
go.drugbank.com/drugs/DB15068
Investigational
Agerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations).
Categories: Heterocyclic Compounds, 2-Ring, Proto-Oncogene Proteins B-raf, antagonists & inhibitors
Drug
ELX-02
go.drugbank.com/drugs/DB15080
Investigational
ELX-02 is under investigation in clinical trial NCT03309605 (Phase 1 Study of ELX-02 in Healthy Adult Subjects).
Categories: Heterocyclic Compounds, 1-Ring
Drug
18-methoxycoronaridine
go.drugbank.com/drugs/DB15096
Investigational
18-methoxycoronaridine is under investigation in clinical trial NCT03084952 (Phase 2 Trial to Evaluate 18-Methoxycoronaridine Efficacy, Safety and Tolerability in Cutaneous Leishmaniasis Patients).
Categories: Heterocyclic Compounds, 2-Ring
Drug
Cusatuzumab
go.drugbank.com/drugs/DB15100
Investigational
[A241975] Cusatuzumab is a humanized IgG1 antibody targeted against CD70. … An overexpression of CD70 can result in the proliferation of malignant cells and has been documented in a variety of solid and hematological malignancies.