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Displaying results 9771 - 9780 of 10000 in total
  1. Drug

    Brodalumab

    go.drugbank.com/drugs/DB11776
    ApprovedInvestigational

    Brodalumab has been used in trials studying the treatment of Asthma, Psoriasis, Crohn's Disease, Psoriatic Arthritis, and Rheumatoid Arthritis. Brodalumab was FDA approved in February, 2017 as Siliq for the treatment of moderate-to-sever...

    Categories: Interleukin-17 Receptor A Antagonist, Interleukin 17 Receptor A Antagonists
  2. Drug

    Danusertib

    go.drugbank.com/drugs/DB11778
    Investigational

    Danusertib has been used in trials studying the treatment of Leukemia.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Tosedostat

    go.drugbank.com/drugs/DB11781
    Investigational

    It has demonstrated anti-tumour activity in a number of models of cancer, both as a single agent and in synergy with cytotoxic agents such as carboplatin and paclitaxel.

  4. Drug

    Anisodamine

    go.drugbank.com/drugs/DB11785
    Investigational

    Anisodamine has been investigated for the treatment of Intestinal Diseases.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  5. Drug

    Ralimetinib

    go.drugbank.com/drugs/DB11787
    Investigational

    Ralimetinib has been used in trials studying the treatment of Postmenopausal, Advanced Cancer, Adult Glioblastoma, Fallopian Tube Cancer, and Metastatic Breast Cancer, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Mirodenafil

    go.drugbank.com/drugs/DB11792
    Investigational

    Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  7. Drug

    Berzosertib

    go.drugbank.com/drugs/DB11794
    Investigational

    Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    GSK-2636771

    go.drugbank.com/drugs/DB11795
    Investigational

    GSK2636771 has been used in trials studying the treatment of CANCER, LYMPHOMA, Solid Neoplasm, Recurrent Solid Neoplasm, and Advanced Malignant Neoplasm, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Tivozanib

    go.drugbank.com/drugs/DB11800
    ApprovedInvestigational

    Marketed by Aveo Oncology, tivozanib is a promising therapy for individuals with RCC who have not been treated successfully with other therapies.[L32524] … Renal cell carcinoma (RCC) is responsible for 3% of cancer cases[A231314] and is one of the 10 most common cancers in adults. The average age of diagnosis is between age 65 to 74.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  10. Drug

    Saracatinib

    go.drugbank.com/drugs/DB11805
    Investigational

    Saracatinib has been investigated for the treatment of Cancer, Osteosarcoma, Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 1-Ring