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SNS01-T
go.drugbank.com/drugs/DB17302InvestigationalSNS01-T is a gene therapy nanoparticle. … It is composed of three components: a B cell-specific plasmid expressing eIF5AK50R; an siRNA that targets the native eIF5A that promotes growth/anti-apoptosis of cancer cells; and polyethylenimine.
Maveropepimut-S
go.drugbank.com/drugs/DB17339InvestigationalMaveropepimut-S is a T cell activating immunotherapy.
MORAb-066
go.drugbank.com/drugs/DB17347InvestigationalMORAb-066 is a humanized antibody directed against tissue factor (TF). It is being investigated in pancreatic cancer.
MB-102 CD123 CAR
go.drugbank.com/drugs/DB17366InvestigationalMB-102 are autologous T cells genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and a truncated human epidermal growth factor receptor.
Gavocabtagene autoleucel
go.drugbank.com/drugs/DB17367InvestigationalGavocabtagene autoleucel is a novel cell therapy consisting of autologous genetically engineered T cells expressing a single-domain antibody that recognizes human Mesothelin, fused to the CD3-epsilon subunit
KAHR-102
go.drugbank.com/drugs/DB17427InvestigationalKAHR-102 is a dual signaling protein fusing cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) to the Fas-ligand (FasL).
BI-1206
go.drugbank.com/drugs/DB17429InvestigationalBI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b.
L-3972-T
go.drugbank.com/drugs/DB17441ExperimentalL-3972-T is one of the components of the human papilloma virus (HPV) type 16 E6/E7 synthetic long peptide (SLP) vaccine ISA101b.
Synonyms: ISA101B component L-3972-T, Human Papilloma Virus (HPV) Type 16 E6/E7 Synthetic Long Peptide (SLP) Vaccine Component L-3972-TMecbotamab vedotin
go.drugbank.com/drugs/DB17442InvestigationalMecbotamab vedotin is an anti-Axl humanized monoclonal antibody conjugated to monomethyl auristatin E using a cleavable linker (CAB-Axl-ADC).[A255212]
TEL540-548
go.drugbank.com/drugs/DB17461InvestigationalTEL540-548 is a recombinant peptide consisting of the amino acid residues 540 to 548 of the human telomerase reverse transcriptase (hTERT).