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RAP-103
go.drugbank.com/drugs/DB28444ExperimentalRAP-103 is a multi-chemokine receptor antagonist which is orally active.[A274606, A274611]
Alcestobart
go.drugbank.com/drugs/DB28487InvestigationalAlcestobart is a biologic drug. … Alcestobart is under investigation in clinical trial NCT05909904 (A Study of Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell Carcinoma).
Efimosfermin alfa
go.drugbank.com/drugs/DB28564InvestigationalEfimosfermin Alfa is a biologic drug. … Efimosfermin Alfa is under investigation in clinical trial NCT07221188 (A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected
VIR-5500
go.drugbank.com/drugs/DB28578InvestigationalVIR-5500 is a small molecule drug. VIR-5500 is under investigation in clinical trial NCT05997615 (Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer).
VIR-5818
go.drugbank.com/drugs/DB28582InvestigationalVIR-5818 is a biologic drug. … VIR-5818 is under investigation in clinical trial NCT05356741 (To Access the Safety and Effects of Intravenous Administration of VIR-5818 Alone and in Combination With Pembrolizumab in Adult Participants
Adermastat
go.drugbank.com/drugs/DB28906InvestigationalAdermastat is a small molecule drug. … Adermastat is under investigation in clinical trial NCT03858686 (The Effect of FP-025, on Allergen-induced Airway Responses in Mild Eosinophilic House Dust Mite (HDM)-Allergic Asthma.).
Acellular nerve allograft
go.drugbank.com/drugs/DB30293ApprovedInvestigationalApproved by the FDA under a Biologics License Application (BLA) as an acellular nerve scaffold for the treatment of adult and pediatric patients (aged ≥1 month) with sensory, mixed, and motor peripheral … Our team is working on the full update, which will be available soon. [L54673,L54668]
MVR-C5252
go.drugbank.com/drugs/DB30379InvestigationalMVR-C5252 is a biologic drug. MVR-C5252 is under investigation in clinical trial NCT06126744 (Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252).
FRAX716
go.drugbank.com/drugs/DB31795ExperimentalFRAX716 is a group I-specific p21-activated kinase (PAK) inhibitor which dramatically inhibits the phosphorylation of PAK and Mek1.[A274678]
PHB-050
go.drugbank.com/drugs/DB32061ExperimentalPHB-050 is a novel, next-generation anti-IgE antibody designed to block IgE from binding to mast cells, while also rapidly reducing circulating IgE and inhibiting its production. … [L54988] It is under investigation for the treatment of multiple atopic diseases, including food allergies, asthma, and atopic dermatitis.[L54988]