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2X-121
go.drugbank.com/drugs/DB16063Investigational2X-121 is under investigation in clinical trial NCT03562832 (Investigation of Anti-tumour Effect and Tolerability of the PARP Inhibitor 2X-121 in Patients With Metastatic Breast Cancer Selected by the 2X-121 DRP).
Categories: Heterocyclic Compounds, 2-RingSP-420
go.drugbank.com/drugs/DB16069InvestigationalSP-420 is under investigation in clinical trial NCT03801889 (SP-420 in Subjects With Transfusion-dependent Beta-thalassemia or Other Rare Anemias).
Categories: Heterocyclic Compounds, 1-RingZetomipzomib
go.drugbank.com/drugs/DB16070InvestigationalZetomipzomib is under investigation in clinical trial NCT04033926 (A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis).
Categories: Heterocyclic Compounds, 1-RingSynonyms: (2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamideLY2828360
go.drugbank.com/drugs/DB16074InvestigationalLY2828360 is under investigation in clinical trial NCT01319929 (A Study of LY2828360 in Patients With Osteoarthritic Knee Pain).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingFirmonertinib
go.drugbank.com/drugs/DB16087InvestigationalAlflutinib is under investigation in clinical trial NCT03452592 (Efficacy and Safety of Alflutinib in Locally Advanced or Metastatic Non-small Cell Lung Cancer Patients With T790M).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingAnivamersen
go.drugbank.com/drugs/DB16089InvestigationalAnivamersen is under investigation in clinical trial NCT01848106 (A Study to Determine the Efficacy and Safety of REG1 Compared to Bivalirudin in Patients Undergoing PCI).
CX-2009
go.drugbank.com/drugs/DB16090InvestigationalCX-2009 is under investigation in clinical trial NCT03149549 (PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors).
Bafisontamab
go.drugbank.com/drugs/DB16091InvestigationalEMB-01 is under investigation in clinical trial NCT03797391 (A Dose Escalation Study of EMB-01 in Participants With Advanced/metastatic Solid Tumors).
Synonyms: Anti-egfr/c-met bispecific antibody emb-01, Anti-egfr/anti-c-met bispecific antibody emb-01Simlukafusp alfa
go.drugbank.com/drugs/DB16092InvestigationalRO6874281 is under investigation in clinical trial NCT03193190 (A Study of Multiple Immunotherapy-based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-pancreatic
Synonyms: Anti-fap/interleukin-2 fusion protein ro6874281APG-1387
go.drugbank.com/drugs/DB16095InvestigationalAPG-1387 is under investigation in clinical trial NCT04568265 (A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B).
Categories: Heterocyclic Compounds, 1-Ring