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Sapablursen
go.drugbank.com/drugs/DB18608InvestigationalSapablursen is a synthetic 2'-O-(2-methoxyethyl)-modified antisense oligonucleotide linked to a tri-antennary cluster of N-acetyl galactosamine (GalNAc3) sugars targeting transmembrane protease, serine
WU-CART-007
go.drugbank.com/drugs/DB18617InvestigationalWU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Synonyms: an allogeneic, fratricide-resistant genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7OTL-203
go.drugbank.com/drugs/DB18643InvestigationalOTL-203 is an autologous CD34+ enriched cell therapy that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase gene.
Synonyms: Autologous CD34+ enriched cell population that contains hematopoietic stem and progenitor cells transduced ex-vivo using a lentiviral vector encoding alpha-L-iduronidase geneEx vivo expanded autologous human corneal epithelial cells containing stem cells
go.drugbank.com/drugs/DB18660ApprovedWithdrawnHoloclar (_ex vivo_ expanded autologous human corneal epithelial cells containing stem cells) is a stem cell therapy used to treat limbal stem cell deficiencies.[L48375]
Cellspan Esophageal Implant
go.drugbank.com/drugs/DB18688ExperimentalThe Cellspan Esophageal ImplantTM (CEI) composes of autologous adipose-derived mesenchymal stromal cells (Ad-MSC) seeded onto a polyurethane tubular mesh cell delivery device.
ISA101b
go.drugbank.com/drugs/DB18694InvestigationalISA101b (peltopepimut-S) is a therapeutic vaccine against the HPV-specific E6/E7 oncoproteins.
Metelimumab
go.drugbank.com/drugs/DB18695ExperimentalMetelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Irpagratinib
go.drugbank.com/drugs/DB18732InvestigationalIrpagratinib (ABSK011) is a highly selective inhibitor of fibroblast growth factor receptor (FGFR) 4.
Diaminopyrimidine oxide
go.drugbank.com/drugs/DB18756ApprovedDiaminopyrimidine oxide is a compound similar to [minoxidil] which is used to aid in hair growth.
Sacituzumab tirumotecan
go.drugbank.com/drugs/DB18777InvestigationalSacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to a topoisomerase I inhibitor.