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  1. Drug

    Bendamustine

    go.drugbank.com/drugs/DB06769
    ApprovedInvestigational

    Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. … Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases resulting in cell death.

    Synonyms: Bendamustine, BendamustinaSalts: Bendamustine hydrochloride, Bendamustine hydrochloride monohydrate
  2. Drug

    Tinostamustine

    go.drugbank.com/drugs/DB15147
    Investigational

    Tinostamustine is under investigation in clinical trial NCT03452930 (Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma).

    Salts: Tinostamustine hydrochloride