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Nirsevimab
go.drugbank.com/drugs/DB16258
ApprovedInvestigational
Nirsevimab (MEDI8897) is a recombinant human immunoglobulin G1 kappa (IgG1ΔΈ) monoclonal antibody used to prevent respiratory syncytial virus (RSV) lower respiratory tract disease in neonates and infants. It binds to the prefusion conformation of the RSV F protein, a glycoprotein involved in the membrane fusion step ...
Clesrovimab
go.drugbank.com/drugs/DB18877ApprovedInvestigational[L53233] As there are no RSV vaccines approved for infant patients, nor are vaccines immediately effective in this population, clesrovimab and similar monoclonal antibodies like [nirsevimab] are designed