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Cyclophosphamide
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause ste...
Docetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigationalDocetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule a...
Synonyms: Docetaxel anhydrousProducts: Docetaxel Anhydrous, Docetaxel anhydrousCyclophosphamide Metabolism Pathway
smpdb.ca/view/SMP0000604Drug metabolismCyclophosphamide is an alkylating agent used in the treatment of certain cancers. … Following absorption, cyclophosphamide is converted into 4-hydroxyphosphamide by a variety of cytochrome P450 isozymes in the liver. 4-Hydroxyphosphamide is more soluble than cyclophosphamide and is the
Cyclophosphamide Action Pathway
smpdb.ca/view/SMP0000447Drug actionCyclophosphamide is an alkylating agent used in the treatment of certain cancers. … Following absorption, cyclophosphamide is converted into 4-hydroxyphosphamide by a variety of cytochrome P450 isozymes in the liver. 4-Hydroxyphosphamide is more soluble than cyclophosphamide and is the
Cyclophosphamide Action Pathway (New)
smpdb.ca/view/SMP0122835Drug actionCyclophosphamide is an antineoplastic alkylating agent used to treat lymphoma and leukemia. … Because the metabolism of cyclophosphamide is linked with the production of the active cytotoxic agent, cyclophosphamide induces its own metabolism with results in an increase in blood plasma clearance