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Zolbetuximab

go.drugbank.com/drugs/DB15118
ApprovedInvestigational

Zolbetuximab (previously claudiximab) is a chimeric cytolytic antibody comprising variable regions derived from mouse anti-human claudin-18 isoform 2 monoclonal antibody and constant regions derived from human IgG1. It is specifically targeted against CLDN18.2, a membrane protein normally found in gastric mucosal ce...

  1. Indication

    CLDN 18.2-positive unresectable, locally advanced HER2 negative Gastric Adenocarcinoma

    go.drugbank.com/conditions/DBCOND0171117
    Drugs: Zolbetuximab
  2. Indication

    CLDN 18.2-positive unresectable, locally advanced HER2 negative Gastroesophageal Junction Adenocarcinoma

    go.drugbank.com/conditions/DBCOND0171122
    Drugs: Zolbetuximab
  3. Indication

    CLDN 18.2-positive metastatic HER2 negative Gastric Adenocarcinoma

    go.drugbank.com/conditions/DBCOND0171119
    Drugs: Zolbetuximab
  4. Indication

    CLDN 18.2-positive metastatic HER2 negative Gastroesophageal Junction Adenocarcinoma

    go.drugbank.com/conditions/DBCOND0171124
    Drugs: Zolbetuximab