Sodium-dependent multivitamin transporter

BE0000094ProteinHumansSLC5A6

Sodium-dependent multivitamin transporter that mediates the electrogenic transport of pantothenate, biotin, lipoate and iodide (PubMed:10329687, PubMed:15561972, PubMed:19211916, PubMed:20980265, PubMed:21570947, PubMed:22015582, PubMed:25809983, PubMed:25971966, PubMed:27904971, PubMed:28052864, PubMed:31754459). It is acted on by 3 drugs in DrugBank.

Gene name
SLC5A6
UniProtKB entry
Q9Y289Swiss-Prot
Cellular location
Cell membrane
Residues / weight
635 residues · 68,641 Da
Also known as
hSMVT · Na(+)-dependent multivitamin transporter · SMVT · Solute carrier family 5 member 6

Resolves to

Protein
UniProtQ9Y289UniProt nameSC5A6_HUMAN
Gene
HGNCHGNC:11041NCBI Gene8884GenBank5006439GeneCardsSLC5A6
Pharmacology
KEGGhsa:8884
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sodium-dependent multivitamin transporter, how selective are they, and which programs against it are still in active trials?

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