DB00121ApprovedInvestigationalNutraceuticalSmall molecule
Biotin is a B-complex vitamin found in many multivitamin products. A water-soluble, enzyme co-factor present in minute amounts in every living cell.
- Mechanism
- Curator reviewed
Biotin is necessary for the proper functioning of enzymes that transport carboxyl units and fix carbon dioxide, and is required for various metabolic functions, including gluconeogenesis, lipogenesis, fatty acid biosynthesis, propionate metabolism, and catabolism of branched-chain amino acids.
- Primary indication
- For nutritional supplementation, also for treating dietary shortage or imbalance.Curator reviewed · 2 structured indications
- Formula / weight
- C10H16N2O3S · 244.311 g/mol (avg)
- First approval
- Canada, 1996 · United States, 2001
- Also known as
- Coenzyme R · D-Biotin · Vitamin B7 · Vitamin H
- Brand names
Resolves to
Clinical / RWD
Structure
InChIKey
YBJHBAHKTGYVGT-ZKWXMUAHSA-NSMILES[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2Transporters
What you can answer from here — as of September 23, 2026
8Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
2TransportersSubstrate / inhibitor direction, not just membershipListed above
Which drugs share a target with Biotin, and which of those have an active Phase 3 trial?
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