Cannabinoid receptor 2

BE0000095ProteinHumansCNR2

Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. It is acted on by 24 drugs in DrugBank.

Gene name
CNR2
UniProtKB entry
P34972Swiss-Prot
Cellular location
Cell membrane
Residues / weight
360 residues · 39,680 Da
Also known as
CB-2 · CB2 · CB2A · CB2B · CX5

Resolves to

Protein
UniProtP34972UniProt nameCNR2_HUMAN
Gene
HGNCHGNC:2160NCBI Gene1269GenBank407807GeneCardsCNR2
Pharmacology
IUPHAR/GtoPdb57KEGGhsa:1269
Structure
PDB2KI9PDB5ZTYPDB6KPC
Drugs

What you can answer from here — as of September 07, 2019

24DrugsApproved to experimental, with action, bond type and pharmacological action
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6Clinical trialsTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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71+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cannabinoid receptor 2, how selective are they, and which programs against it are still in active trials?

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