Dronabinol is a synthetic delta-9-THC used in the treatment of anorexia and weight loss in HIV patients as well as nausea and vomiting in cancer chemotherapy. Dronabinol (marketed as Marinol) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana).
- Mechanism
- Curator reviewed
Dronabinol is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana). THC demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R) receptors, which results in the well-known effects of smoking cannabis such as increased appetite, reduced pain, and changes in emotional and cognitive processes.
- Primary indication
- Dronabinol is indicated for the treatment of anorexia associated with weight loss in patients with AIDS, and nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic...Curator reviewed · 2 structured indications
- Formula / weight
- C21H30O2 · 314.4617 g/mol (avg)
- First approval
- Canada, 2003 · United States, 1994
- Also known as
- .DELTA.1-THC · delta 9-tetrahydrocannabinol · delta-9-THC · delta(9)-THC · Tetrahydrocannabinol
- Code names
- ABBOTT-40566 · Dea No. 7369 · Dea No. 7370 · J882F · NSC-134454 · QCD-84924 · SP-104
- Brand names
Resolves to
CYQFCXCEBYINGO-IAGOWNOFSA-NSMILES[H][C@@]12C=C(C)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(CCCCC)=C1What you can answer from here — as of September 23, 2026
Which drugs share a target with Dronabinol, and which of those have an active Phase 3 trial?
Create a free account or log in to explore the full data card.
Create Account