Evolved beta-galactosidase subunit alpha

BE0000116ProteinEscherichia coli (strain K12)ebgA

The wild-type enzyme is an ineffective lactase. It is acted on by 1 drug in DrugBank.

Gene name
ebgA
UniProtKB entry
P06864Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
1,030 residues · 117,878 Da
Also known as
3.2.1.23 · Beta-gal · Lactase

Resolves to

Protein
UniProtP06864UniProt nameBGA2_ECOLI
Gene
NCBI Gene947583GenBank145821
Pharmacology
KEGGecj:JW5511
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Evolved beta-galactosidase subunit alpha, how selective are they, and which programs against it are still in active trials?

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