Cationic amino acid transporter 3

BE0000136ProteinHumansSLC7A3

Uniporter that mediates the uptake of cationic L-amino acids such as L-arginine, L-lysine and L-ornithine (PubMed:11591158). It is acted on by 3 drugs in DrugBank.

Gene name
SLC7A3
UniProtKB entry
Q8WY07Swiss-Prot
Cellular location
Cell membrane
Residues / weight
619 residues · 67,168 Da
Also known as
ATRC3 · CAT-3 · CAT3 · Cationic amino acid transporter y+ · Solute carrier family 7 member 3

Resolves to

Protein
UniProtQ8WY07UniProt nameCTR3_HUMAN
Gene
HGNCHGNC:11061NCBI Gene84889GenBank17224957GeneCardsSLC7A3
Pharmacology
KEGGhsa:84889
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Cationic amino acid transporter 3, how selective are they, and which programs against it are still in active trials?

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