Carnitine O-palmitoyltransferase 2, mitochondrial

BE0000179ProteinHumansCPT2

Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites (PubMed:20538056, PubMed:24780397). It is acted on by 2 drugs in DrugBank.

Gene name
CPT2
UniProtKB entry
P23786Swiss-Prot
Cellular location
Mitochondrion inner membrane
Residues / weight
658 residues · 73,776 Da
Also known as
2.3.1.21 · Carnitine palmitoyltransferase II · CPT II · CPT1

Resolves to

Protein
UniProtP23786UniProt nameCPT2_HUMAN
Gene
HGNCHGNC:2330NCBI Gene1376GenBank1041195GeneCardsCPT2
Pharmacology
KEGGhsa:1376
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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5Clinical trialsTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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38+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Carnitine O-palmitoyltransferase 2, mitochondrial, how selective are they, and which programs against it are still in active trials?

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