DNA-directed RNA polymerase subunit beta'

BE0000186ProteinMycobacterium tuberculosisrpoC

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is acted on by 4 drugs in DrugBank.

Gene name
rpoC
UniProtKB entry
P9WGY7Swiss-Prot
Residues / weight
1,316 residues · 146,768 Da
Also known as
2.7.7.6 · RNA polymerase subunit beta' · RNAP subunit beta' · Transcriptase subunit beta'

Resolves to

Protein
UniProtP9WGY7UniProt nameRPOC_MYCTU
Gene
NCBI Gene888177
Pharmacology
KEGGmtu:Rv0668
Structure
PDB5UH5PDB5UH6PDB5UH7
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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5Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on DNA-directed RNA polymerase subunit beta', how selective are they, and which programs against it are still in active trials?

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