Aspartoacylase

BE0000187ProteinHumansASPA

Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. It is acted on by 5 drugs in DrugBank.

Gene name
ASPA
UniProtKB entry
P45381Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
313 residues · 35,735 Da
Also known as
3.5.1.15 · ACY-2 · ACY2 · Aminoacylase-2 · ASP

Resolves to

Protein
UniProtP45381UniProt nameACY2_HUMAN
Gene
HGNCHGNC:756NCBI Gene443GenBank455834GeneCardsASPA
Pharmacology
KEGGhsa:443
Structure
PDB2I3CPDB2O4HPDB2O53
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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29+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aspartoacylase, how selective are they, and which programs against it are still in active trials?

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