Aldehyde dehydrogenase family 3 member B2

BE0000193ProteinHumansALDH3B2

Oxidizes medium and long chain fatty aldehydes in lipid droplets into non-toxic fatty acids. It is acted on by 2 drugs in DrugBank.

Gene name
ALDH3B2
UniProtKB entry
P48448Swiss-Prot
Cellular location
Lipid droplet
Residues / weight
385 residues · 42,635 Da
Also known as
1.2.1.3 · Aldehyde dehydrogenase 8 · ALDH3B2 · ALDH8 · Long-chain fatty aldehyde dehydrogenase

Resolves to

Protein
UniProtP48448UniProt nameAL3B2_HUMAN
Gene
HGNCHGNC:411NCBI Gene222GenBank1051281GeneCardsALDH3B2
Pharmacology
KEGGhsa:222
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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1Metabolic reactionDrug transformations it catalyses, substrate to product
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Aldehyde dehydrogenase family 3 member B2, how selective are they, and which programs against it are still in active trials?

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