Folate receptor beta

BE0000271ProteinHumansFOLR2

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. It is acted on by 3 drugs in DrugBank.

Gene name
FOLR2
UniProtKB entry
P14207Swiss-Prot
Cellular location
Cell membrane
Residues / weight
255 residues · 29,279 Da
Also known as
FBP · Folate receptor 2 · Folate receptor, fetal/placental · FR-beta · Placental folate-binding protein

Resolves to

Protein
UniProtP14207UniProt nameFOLR2_HUMAN
Gene
HGNCHGNC:3793NCBI Gene2350GenBank1655592GeneCardsFOLR2
Pharmacology
KEGGhsa:2350
Structure
PDB4KMYPDB4KMZPDB4KN0
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
2Clinical trialsTrials of drugs acting on it, by phase and status
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
19+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Folate receptor beta, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In