RNA-directed RNA polymerase catalytic subunit

BE0000282ProteinInfluenza A virus (strain A/Beijing/11/1956 H1N1)PB1

RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments. It is acted on by 2 drugs in DrugBank.

Gene name
PB1
UniProtKB entry
P16502Swiss-Prot
Cellular location
Host nucleus
Residues / weight
757 residues · 86,535 Da
Also known as
2.7.7.48 · PB1 · Polymerase basic protein 1 · RNA-directed RNA polymerase subunit P1

Resolves to

Protein
UniProtP16502UniProt nameRDRP_I56A0
Gene
GenBank324960
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which approved drugs act on RNA-directed RNA polymerase catalytic subunit, how selective are they, and which programs against it are still in active trials?

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