Glutathione reductase

BE0000298ProteinEscherichia coli (strain K12)gor

Maintains high levels of reduced glutathione in the cytosol. It is acted on by 2 drugs in DrugBank.

Gene name
gor
UniProtKB entry
P06715Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
450 residues · 48,772 Da
Also known as
1.8.1.7 · GR

Resolves to

Protein
UniProtP06715UniProt nameGSHR_ECOLI
Gene
NCBI Gene948014GenBank146248
Pharmacology
KEGGecj:JW3467
Structure
PDB1GERPDB1GESPDB1GET
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Glutathione reductase, how selective are they, and which programs against it are still in active trials?

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