Flavin adenine dinucleotide

DB03147ApprovedSmall molecule

Flavin adenine dinucleotide is a coenzyme form of vitamin B2 used in clinical conditions associated with vitamin B2 deficiency. A condensation product of riboflavin and adenosine diphosphate.

Mechanism: Pharmacologically active on Nitric oxide synthase 1, Dihydropyrimidine dehydrogenase [NADP(+)], and Xanthine dehydrogenase/oxidase
Curator reviewed
Primary indication: Used to treat eye diseases caused by vitamin B2 deficiency, such as keratitis and blepharitis.Curator reviewed · 2 structured indications
Formula / weight: C₂₇H₃₃N₉O₁₅P₂ · 785.5497 g/mol (avg)
First approval: United States, 2015
Also known as: Flavin-Adenine Dinucleotide · Flavine adenine dinucleotide
Brand names: EnBrace HR
EnLyte

Resolves to

Compound

UNIIZC44YTI8KKCAS146-14-5ChEMBLCHEMBL1232653ChEBI16238PubChem643975KEGGD00005

Clinical / RWD

RxNorm1314412

Structure

InChIKeyVWWQXMAJTJZDQX-UYBVJOGSSA-NSMILES

CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2

Targets

P29475NOS1Q12882DPYDP47989XDHP15559NQO1P21397MAOAQ16881TXNRD1P27338MAOBP00390GSR+78 more

What you can answer from here — as of September 13, 2026

86Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

2Structured indicationsCondition, population, route and combination as fields, not prose

7Marketed productsAcross 1 country and 3 labellers

83+ReferencesStructured and connected to the statements they support

Which drugs share a target with Flavin adenine dinucleotide, and which of those have an active Phase 3 trial?

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