SEC14-like protein 3
Details
- Name
- SEC14-like protein 3
- Kind
- protein
- Synonyms
- TAP2
- Tocopherol-associated protein 2
- Gene Name
- SEC14L3
- UniProtKB Entry
- Q9UDX4Swiss-Prot
- Organism
- Humans
- NCBI Taxonomy ID
- 9606
- Amino acid sequence
>lcl|BSEQ0000675|SEC14-like protein 3 MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYM EFRKTMDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDL LKTKMRDCERILHECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEE NYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLGNNWKEGLLKLISPEELPAQ FGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQINRGSSHQVEYEILFPG CVLRWQFSSDGADIGFGVFLKTKMGERQRAGEMTDVLPSQRYNAHMVPEDGNLTCSEAGV YVLRFDNTYSFVHAKKVSFTVEVLLPDEGMQKYDKELTPV
- Number of residues
- 400
- Molecular Weight
- 46047.835
- Theoretical pI
- 5.97
- GO Classification
- Componentscytoplasm
- General Function
- Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids
- Specific Function
- lipid binding
- Pfam Domain Function
- CRAL_TRIO (PF00650)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0010254|SEC14-like protein 3 (SEC14L3) ATGGTGATCCAGAAGTACATGCCTGGGGGCCTGTGTGGCTATGACCGTGATGGCTGCCCC GTGTGGTATGACATCATTGGGCCACTTGATCCCAAGGGGTTGCTCTTCTCAGTCACCAAG CAGGACCTGCTCAAGACCAAGATGAGGGACTGTGAGCGCATCCTGCATGAGTGTGACCTG CAGACAGAGAGGCTAGGGAAGAAGATTGAGACCATCGTGATGATATTTGACTGTGAGGGC CTGGGACTGAAACACTTCTGGAAACCTCTGGTAGAAGTGTACCAGGAGTTCTTTGGCCTC CTTGAAGAGAATTACCCAGAGACCCTGAAGTTCATGCTCATCGTGAAAGCTACCAAACTG TTCCCTGTGGGCTACAACCTCATGAAGCCATTCCTGAGTGAGGACACTCGCAGGAAAATT ATTGTGTTGGGAAATAACTGGAAGGAAGGTTTGCTGAAACTCATCAGTCCTGAGGAACTG CCTGCCCAGTTTGGGGGCACCCTGACTGACCCAGATGGGAACCCCAAATGTTTAACCAAG ATTAACTATGGCGGGGAGATCCCCAAGTCCATGTACGTGCGGGACCAGGTGAAGACTCAG TACGAGCACTCGGTGCAGATCAACCGCGGCTCATCACACCAAGTGGAATACGAGATCCTA TTTCCAGGCTGCGTTCTCAGGTGGCAGTTCTCATCTGATGGTGCGGACATCGGCTTCGGA GTTTTCCTGAAGACCAAGATGGGGGAGCGACAGCGGGCAGGGGAGATGACAGATGTTCTA CCCAGCCAGCGCTATAACGCCCACATGGTGCCCGAGGATGGGAACCTCACCTGCTCAGAG GCCGGCGTCTATGTCCTACGCTTCGACAACACCTATAGCTTTGTCCACGCCAAGAAGGTC AGCTTCACAGTGGAGGTCCTGCTCCCTGACGAGGGCATGCAGAAATATGATAAGGAGCTC ACCCCTGTCTAG
- Chromosome Location
- 22
- Locus
- 22q12.2
- External Identifiers
Resource Link UniProtKB ID Q9UDX4 UniProtKB Entry Name S14L3_HUMAN GenBank Protein ID 27803382 GenBank Gene ID AY158086 GeneCard ID SEC14L3 GenAtlas ID SEC14L3 HGNC ID HGNC:18655 PDB ID(s) 4UYB KEGG ID hsa:266629 NCBI Gene ID 266629 - General References
- Kempna P, Zingg JM, Ricciarelli R, Hierl M, Saxena S, Azzi A: Cloning of novel human SEC14p-like proteins: ligand binding and functional properties. Free Radic Biol Med. 2003 Jun 1;34(11):1458-72. [Article]
- Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al.: The DNA sequence of human chromosome 22. Nature. 1999 Dec 2;402(6761):489-95. [Article]
- Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Vitamin E approved, nutraceutical, vet_approved unknown target Details alpha-Tocopherol succinate approved, nutraceutical, vet_approved unknown target Details D-alpha-Tocopherol acetate approved, nutraceutical, vet_approved unknown target Details Tocopherol approved, investigational no transporter substrate Details alpha-Tocopherol acetate approved no transporter substrate Details Tocofersolan approved no transporter substrate Details Vitamin E approved, nutraceutical, vet_approved unknown carrier binder Details