Protein amnionless

BE0000340ProteinHumansAMN

Membrane-bound component of the endocytic receptor formed by AMN and CUBN (PubMed:14576052, PubMed:29402915, PubMed:30523278). It is acted on by 2 drugs in DrugBank.

Gene name
AMN
UniProtKB entry
Q9BXJ7Swiss-Prot
Cellular location
Apical cell membrane
Residues / weight
453 residues · 47,754 Da

Resolves to

Protein
UniProtQ9BXJ7UniProt nameAMNLS_HUMAN
Gene
HGNCHGNC:14604NCBI Gene81693GenBank13507259GeneCardsAMN
Pharmacology
KEGGhsa:81693
Structure
PDB6GJE
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Protein amnionless, how selective are they, and which programs against it are still in active trials?

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