Antizyme inhibitor 2

BE0000448ProteinHumansAZIN2

Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. It is acted on by 3 drugs in DrugBank.

Gene name
AZIN2
UniProtKB entry
Q96A70Swiss-Prot
Cellular location
Nucleus
Residues / weight
460 residues · 49,979 Da
Also known as
ADC · ARGDC · Arginine decarboxylase · AzI2 · KIAA1945

Resolves to

Protein
UniProtQ96A70UniProt nameAZIN2_HUMAN
Gene
HGNCHGNC:29957NCBI Gene113451GenBank15858863GeneCardsAZIN2
Pharmacology
KEGGhsa:113451
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
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21GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Antizyme inhibitor 2, how selective are they, and which programs against it are still in active trials?

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