Voltage-gated inwardly rectifying potassium channel KCNH6

BE0000462ProteinHumansKCNH6

Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. It is acted on by 2 drugs in DrugBank.

Gene name
KCNH6
UniProtKB entry
Q9H252Swiss-Prot
Cellular location
Cell membrane
Residues / weight
958 residues · 106,424 Da
Also known as
Eag-related protein 2 · ERG-2 · ERG2 · Ether-a-go-go-related gene potassium channel 2 · Ether-a-go-go-related protein 2

Resolves to

Protein
UniProtQ9H252UniProt nameKCNH6_HUMAN
Gene
HGNCHGNC:18862NCBI Gene81033GenBank11878259GeneCardsKCNH6
Pharmacology
IUPHAR/GtoPdb573KEGGhsa:81033
Drugs

What you can answer from here — as of October 08, 2024

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Voltage-gated inwardly rectifying potassium channel KCNH6, how selective are they, and which programs against it are still in active trials?

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