ATP synthase F(1) complex subunit delta, mitochondrial

BE0000484ProteinHumansATP5F1D

Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron... It is acted on by 3 drugs in DrugBank.

Gene name
ATP5F1D
UniProtKB entry
P30049Swiss-Prot
Cellular location
Mitochondrion
Residues / weight
168 residues · 17,490 Da
Also known as
ATP synthase F1 subunit delta · ATP5D · F-ATPase delta subunit

Resolves to

Protein
UniProtP30049UniProt nameATPD_HUMAN
Gene
HGNCHGNC:837NCBI Gene513GenBank12586GeneCardsATP5F1D
Pharmacology
KEGGhsa:513
Structure
PDB8H9FPDB8H9JPDB8H9M
Drugs

What you can answer from here — as of June 26, 2025

3DrugsApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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12+ReferencesStructured and connected to the statements they support
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Which approved drugs act on ATP synthase F(1) complex subunit delta, mitochondrial, how selective are they, and which programs against it are still in active trials?

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