Potassium voltage-gated channel subfamily E member 1

BE0000489ProteinHumansKCNE1

Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. It is acted on by 2 drugs in DrugBank.

Gene name
KCNE1
UniProtKB entry
P15382Swiss-Prot
Cellular location
Cell membrane
Residues / weight
129 residues · 14,675 Da
Also known as
Delayed rectifier potassium channel subunit IsK · IKs producing slow voltage-gated potassium channel subunit beta Mink · Minimal potassium channel · MinK

Resolves to

Protein
UniProtP15382UniProt nameKCNE1_HUMAN
Gene
HGNCHGNC:6240NCBI Gene3753GenBank386838GeneCardsKCNE1
Pharmacology
KEGGhsa:3753
Structure
PDB2K21PDB9U7FPDB9UC8
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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24GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Potassium voltage-gated channel subfamily E member 1, and which indications are they being tested in?

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