Ambasilide

DB19463ExperimentalSmall molecule

Ambasilide is a small molecule drug. The usage of the INN stem '-ilide' in the name indicates that Ambasilide is a sematilide derivative class III antiarrhythmic. Ambasilide has a monoisotopic...

Mechanism: Pharmacologically active on Voltage-gated inwardly rectifying potassium channel KCNH2, Potassium voltage-gated channel subfamily E member 1, and Potassium voltage-gated channel subfamily KQT member 1
Curator reviewed
Formula / weight: C₂₁H₂₅N₃O · 335.451 g/mol (avg)

Resolves to

Compound

UNII012LYD6KXMCAS83991-25-7

Structure

InChIKeyDLNAKYFPFYUBDR-HDICACEKSA-NSMILES[H][C@]12CN(CC3=CC=CC=C3)C[C@]([H])(CN(C1)C(=O)C1=CC=C(N)C=C1)C2

Targets

Q12809KCNH2P15382KCNE1P51787KCNQ1P48549KCNJ3P48544KCNJ5Q9UK17KCND3P63252KCNJ2

What you can answer from here — as of August 30, 2026

7Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

7+ReferencesStructured and connected to the statements they support

Which drugs share a target with Ambasilide, and which of those have an active Phase 3 trial?

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