Glutamate receptor ionotropic, NMDA 3B

BE0000534ProteinHumansGRIN3B

Component of a non-conventional N-methyl-D-aspartate (NMDA) receptors (NMDARs) that function as heterotetrameric, ligand-gated cation channels with low calcium permeability and low voltage-dependent block by Mg(2+) (By similarity). It is acted on by 4 drugs in DrugBank.

Gene name
GRIN3B
UniProtKB entry
O60391Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,043 residues · 112,991 Da
Also known as
GluN3B · N-methyl-D-aspartate receptor subtype 3B · NMDAR3B · NR3B

Resolves to

Protein
UniProtO60391UniProt nameNMD3B_HUMAN
Gene
HGNCHGNC:16768NCBI Gene116444GenBank3025446GeneCardsGRIN3B
Pharmacology
KEGGhsa:116444
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
15GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
9+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Glutamate receptor ionotropic, NMDA 3B, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In